Description

Cefuroxime Axetil 500mg Tablet
Broad-Spectrum. Trusted. Powerful.
10 tablets in a Mono-Pack,
🧪 Composition

Each film-coated tablet contains:
Cefuroxime Axetil IP 500 mg (equivalent to Cefuroxime 500 mg)

🔬 Therapeutic Class

💥 Second-generation Cephalosporin Antibiotic

📌 Indications

Safurix-500 is indicated in the treatment of a wide range of bacterial infections, including:
• Upper Respiratory Tract Infections
➤ Pharyngitis, Tonsillitis, Sinusitis, Otitis Media
• Lower Respiratory Tract Infections
➤ Acute Bronchitis, Exacerbations of Chronic Bronchitis, Pneumonia
• Urinary Tract Infections
➤ Cystitis, Pyelonephritis

• Skin & Soft Tissue Infections
• Uncomplicated Gonorrhea
• Bone and Joint Infections

⚙ Mechanism of Action

Cefuroxime Axetil is a bactericidal agent that acts by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins (PBPs) ➤ Leading to bacterial lysis and death.

✅ Key Features of Safurix-500

🌐 Broad-spectrum activity – effective against both Gram-positive and Gram-negative organisms.
⚡ Rapid onset of action with strong tissue penetration.
🛡 Stable against many beta-lactamases – resistant to bacterial resistance.
🍽 Better oral bioavailability when taken after food.
📉 Proven clinical efficacy in community-acquired respiratory infections.

🧾 Dosage & Administration

Adults: 250–500mg twice daily, depending on infection severity.
Duration: 5–10 days (or as advised by the physician).
🕒 Administer after meals for optimal absorption.

💊 Pharmacokinetic Highlights
• Peak plasma levels in 2–3 hours
• Half-life ~1.2 hours
• Eliminated unchanged in urine – excellent for UTIs

🧬 Sensitive Pathogens

✔ Streptococcus pneumoniae
✔ Haemophilus influenzae
✔ E. coli
✔ Klebsiella spp.
✔ Moraxella catarrhalis
✔ Staphylococcus aureus (MSSA)

⚠ Adverse Effects

🔹 Mild GI upset (nausea, diarrhea)
🔹 Rare hypersensitivity reactions
🔹 Use cautiously in patients with penicillin allergy

🔒 Storage

Store in a cool, dry place, away from light and moisture.

👨‍⚕ WHY PRESCRIBE SAFURIX-500?

✅ Clinically Reliable for common OPD infections
✅ Excellent Tolerability & Patient Compliance
✅ Backed by Global Clinical Experience

🏥 Recommended In:

ENT | Pulmonology | Urology | Dermatology | General Medicine

🏷 Available Pack:

Box of 10 tablets in Alu-Alu strip

🔹 Safurix-500 – Targeting Infection at its Root.
Backed by Science. Trusted by Doctors.
💊 Safurix-500

Cefuroxime Axetil 500mg Tablet
Broad-Spectrum. Trusted. Powerful.
10 tablets in a Mono-Pack, MRP-495/-

🧪 Composition

Each film-coated tablet contains:
Cefuroxime Axetil IP 500 mg (equivalent to Cefuroxime 500 mg)

🔬 Therapeutic Class

💥 Second-generation Cephalosporin Antibiotic

📌 Indications

Safurix-500 is indicated in the treatment of a wide range of bacterial infections, including:
• Upper Respiratory Tract Infections
➤ Pharyngitis, Tonsillitis, Sinusitis, Otitis Media
• Lower Respiratory Tract Infections
➤ Acute Bronchitis, Exacerbations of Chronic Bronchitis, Pneumonia
• Urinary Tract Infections
➤ Cystitis, Pyelonephritis

• Skin & Soft Tissue Infections
• Uncomplicated Gonorrhea
• Bone and Joint Infections

⚙ Mechanism of Action

Cefuroxime Axetil is a bactericidal agent that acts by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins (PBPs) ➤ Leading to bacterial lysis and death.

✅ Key Features of Safurix-500

🌐 Broad-spectrum activity – effective against both Gram-positive and Gram-negative organisms.
⚡ Rapid onset of action with strong tissue penetration.
🛡 Stable against many beta-lactamases – resistant to bacterial resistance.
🍽 Better oral bioavailability when taken after food.
📉 Proven clinical efficacy in community-acquired respiratory infections.

🧾 Dosage & Administration

Adults: 250–500mg twice daily, depending on infection severity.
Duration: 5–10 days (or as advised by the physician).
🕒 Administer after meals for optimal absorption.

💊 Pharmacokinetic Highlights
• Peak plasma levels in 2–3 hours
• Half-life ~1.2 hours
• Eliminated unchanged in urine – excellent for UTIs

🧬 Sensitive Pathogens

✔ Streptococcus pneumoniae
✔ Haemophilus influenzae
✔ E. coli
✔ Klebsiella spp.
✔ Moraxella catarrhalis
✔ Staphylococcus aureus (MSSA)

⚠ Adverse Effects

🔹 Mild GI upset (nausea, diarrhea)
🔹 Rare hypersensitivity reactions
🔹 Use cautiously in patients with penicillin allergy

🔒 Storage

Store in a cool, dry place, away from light and moisture.

👨‍⚕ WHY PRESCRIBE SAFURIX-500?

✅ Clinically Reliable for common OPD infections
✅ Excellent Tolerability & Patient Compliance
✅ Backed by Global Clinical Experience

🏥 Recommended In:

ENT | Pulmonology | Urology | Dermatology | General Medicine

🏷 Available Pack:

Box of 10 tablets in Alu-Alu strip

🔹 Safurix-500 – Targeting Infection at its Root.
Backed by Science. Trusted by Doctors.